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2016 Hyperchloremia and diuretic resistance in heart failure: Mechanistic insights This is a two-part study by translational researchers at Yale seeking to clarify the role of hypochloremia in heart failure

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Clearance rate varies by subject metabolism, injection site, and dose magnitude higher doses (500mcg) may remain detectable for up to 24 hours, while lower doses (100200mcg) clear more rapidly

Bourgault S, Choi S, Buxbaum JN, Kelly JW, Price JL, Reixach N