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X.C: Investigation

Safety Findings and Adverse Events In terms of safety, treatment-emergent adverse events (TEAEs) were reported in the majority of participants across all groups

To date, however, most of the aforementioned results have come from animal models, with limited human randomized controlled trials

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This trend is in contrast to the rxYFP fusion constructs with mono- and dithiol variants of ScGrx1, which were shown to react more rapidly with GSSG when the second cysteinyl residue was replaced by serine (Table 1) 31

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