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High costs The analysis found that the most common factor influencing the likelihood of discontinuation was age, with younger users aged 18-29 years 48% more likely to stop treatment within the first year than those aged 45-59 years, after controlling for sex differences
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Most patients received 3.0 mg at first dispensation (78% and 68% in cohorts 1 and 2, respectively)
Additionally, alcohol can impair awareness of hypoglycemic symptoms, making it more difficult for patients to recognize and respond to low blood sugar
With the majority of people expressing interest in the new obesity treatment not being previous users of weight-loss injections, this indicated that the new pill could widen access to millions of people across the country
It is also, per recent mechanistic work, responsible for PCSK9 degradation, which is the likely pathway behind the LDL cholesterol reductions seen in TRIUMPH-4
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