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Clinical studies in humans have not been published so far (41, 51)

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Building on these advances, combination strategies with antiviral and antifibrotic agents warrant systematic clinical investigationrecent studies have shown that glycyrrhizin combined with entecavir significantly improves liver function and reduces fibrosis markers in chronic hepatitis B, while its combination with Wuzhi capsule demonstrates superior efficacy in non-alcoholic steatohepatitis (Li, 2025