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The 2024 Journal of Cosmetic Dermatology commentary by Andriotis and Dayan (PMC11845967) explicitly recommended this combination approach, noting that effective management of facial volume loss, skin laxity, and body contour challenges following GLP-1 weight loss requires a combination of injectable treatments, energy-based devices, and in some cases surgical interventions

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People eating in a consistent calorie surplus will not see meaningful fat reduction regardless of hormone levels