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421,425,430 Studies have demonstrated greater cardiac autonomic dysfunction in PDPN than in painless DPN, 421,427,431 while others found no association

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This suggests that chlorogenic lactones might contribute to the increased protective effects against H2O2-induced death of neuron cells (Chu, 2009)

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smFISH was performed as described by Stellaris RNA FISH frozen tissue protocol (LGC Biosearch Technologies) and a previous publication 67 with minor modifications