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We found that liraglutide dosed animals showed no significant differences in disease progression when compared to vehicle dosed animals in either the SOD1 G93A or TDP-43 Q331K mouse models of ALS

95% CI, 0.82-0.92)

doi: 10.1017/cjn.2017.284 48

As expected, blocking the PTHR1 completely normalized calcium levels, reduced CTX-1 levels and increased P1NP levels, without significantly altering PTHrP levels (Extended data Fig

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The researchers believe that the fluidity of the cell membrane mainly depends on the lipid bilayer