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In contrast, in CD8 T cells and natural killer (NK) cells, prolonged immune and metabolic signals cause lipid metabolism dysregulation, which impairs their antitumor potency [55]

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DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of alzheimers disease

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Data obtained in experimental studies need to be confirmed in larger clinical trials

Dapagliflozin exerts anti-inflammatory effects via inhibition of LPS-induced TLR-4 overexpression and NF-kappaB activation in human endothelial cells and differentiated macrophages