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En los ensayos clnicos SURMOUNT y SURPASS, los efectos adversos ms frecuentes de la Tirzepatida fueron gastrointestinales: nuseas (18-22%), diarrea (14-17%), vmito (9-12%) y estreimiento (8-12%), concentrados principalmente en las primeras semanas

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These changes ultimately result in the exocytosis of insulin-containing secretory granules

and final approval of the article

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Possible role of PHD inhibitors as hypoxia-mimicking agents in the maintenance of neural stem cells' self-renewal properties