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Despite the marked importance of APOE4 as a risk factor and key feature in the pathogenesis of AD, there have been few therapeutics that specifically address this target

In the study by Kong et al

From that filing date, the drug must travel through preclinical toxicology (four to seven years), Phase I through Phase III clinical trials (six to eight years), and FDA review of the New Drug Application or Biologics License Application (six months to two years)