29 With semaglutide, body weight is reported to stabilise after 52104 weeks of treatment, 30 limiting our opportunity to assess skeletal adaptions overshoots after stabilisation of body weight
Second, the off-label adoption pattern that the longevity reframing will inevitably accelerate is going to produce the next wave of monitoring, dosing, and selection problems, patients without obesity or diabetes do not have the diagnostic anchors (BMI, A1c, insulin resistance markers) that frame the on-label conversation, and the clinical infrastructure for managing GLP-1 therapy in metabolically healthy users is, charitably described, thin
Concerns around side effects, long-term safety, cost and whether medication feels necessary in the first place all play their part in informing how people feel about starting weight loss treatments
Women of childbearing potential should use effective contraception and stop Wegovy at least 2 months before a planned pregnancy
Concerning nausea looks different
Science Day is a hearing in mass tort cases where both sides present evidence, often including scientific studies, key documents, and expert testimonies
