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Model building, refinement, and validation Model buildings of both c-MET/HGF and c-MET/NK1 complexes were initiated by rigid-body docking of individual domains from the crystal structures of SEMA, PSI, IPT1, and IPT2 domains of c-MET and N, K1, K2, and SPH domains of HGF 14,24,25,30

Wang et al

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The peptide modulates over 4000 human genes, turning up genes associated with tissue remodeling and antioxidant protection while turning down genes linked to inflammation and tissue destruction

2011 Mar 14;88(11-12):535-42