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Boxed Warning Its worth noting that Tirzepatide comes with a boxed warning regarding the risk of thyroid C-cell tumors

Weight regain typically begins when semaglutide levels fall below therapeutic thresholds, usually around weeks 23 after your final dose

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showed that supplementation with Bifidobacterium longum NCC3001 (BL) at a dose of 1 10 10 CFU/day for 4 weeks improves depression-like symptoms (reduced BDI-II score by 3.2 points) and quality of life (increased IBS-QoL score by 15%) in IBS patients with comorbid depressive symptoms (20)