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The GLP-1 revenue stream has been significant for HIMS, but not the only source of growth

Mechanistically, ox-LDL induces lipid peroxidation by inhibiting the SREBP-1/SCD1/FADS2-mediated lipid biosynthesis pathway, leading to endothelial damage and ultimately inducing ferroptosis (46)

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Overall, these three OSMs play a crucial role in the pathogenesis and progression of IBD and have been suggested to serve as potential diagnostic, differential, progression, and prognostic markers in the disease

Baseline characteristics were balanced across GLP-1 receptor agonist and placebo groups, with a median follow-up period of 25.2 months