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Their microarray analysis of RNA obtained from human participants who consumed bi-daily 450 mg of cocoa flavanols revealed that the distinct patterns of differentially expressed genes were correlated with changes in endothelial function, arterial stiffness and blood pressure

Comparators were any of the eligible doses of tirzepatide and semaglutide, placebo, and also other glucose-lowering drugs provided they were directly compared to tirzepatide and semaglutide in at least one trial

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These effects often diminish over time, but monitoring is crucial to ensure patient safety and comfort