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Body mass index (BMI) of 27 or greater with at least one weight-related health condition such as hypertension (high blood pressure), type 2 diabetes mellitus, hypercholesterolemia (high cholesterol), and sleep apnea

Results were confirmed in analyses pooling data with an additional internal replication sample from the same subjects measured at 6-year follow-up (totaling 4141 observations)

(43) Patient Safety and Side Effects Gastrointestinal Issues: Common side effects include nausea, diarrhea, constipation, and vomiting, particularly during dose escalation

Effect of vitamin D supplementation on polycystic ovary syndrome: A meta-analysis