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In people who struggle with obesity or metabolic dysfunction, this signaling system can become sluggish

Less than 1% of the swallowed dose reaches the bloodstream, compared with roughly 89% from the injection

The Lancet 398(10296):262276 Bryant MG, Bloom SR, Polak JM, Hobbs S, Domschke W, Domschke S et al (1983) Measurement of gut hormonal peptides in biopsies from human stomach and proximal small intestine

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