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Additionally, PAI-1 not only acts as a key mediator of TGF--induced senescence but also forms a cascade amplification effect through the activation of the p53-p21-retinoblastoma (Rb) protein signaling axis, ultimately leading to AT2 cell senescence [72, 73]

Aldosterone-regulated sodium transport and blood pressure

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Marty L, Bausewein D, Mller C, Bangash SAK, Moseler A, Schwarzlnder M, Mller-Schssele SJ, Zechmann B, Riondet C, Balk J, Wirtz M, Hell R, Reichheld J-P, Meyer AJ (2019) Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems

53(6):274 to 278

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