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In addition, heterogenous tumors are composed of multiple subpopulations associated with different proliferative and malignant potentials [36]

Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH) is a pentapeptide of the growth-hormone-secretagogue class that acts in vitro as a selective agonist of GHS-R1a, the receptor for endogenous ghrelin

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