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During bariatric surgery, the stomach is surgically constricted, so food bypasses the stomach and travels to the lower part of the small intestine, the home of molecules that regulate the secretion of GLP-1

During DPP-4 inhibition, levels of active GLP-1 increase up to 2-3 times

Inhibition of the Xc-system determines the decrease in GSH levels, which indirectly leads to the inactivation of GPX4 and the onset of ferroptosis (Ingold et al., 2018

NACET Pretreatment Protects RPE Cells from Oxidative Stress In the experiments described above, NAC and NACET exerted their protective effect both by directly reacting with the oxidative stress generators and by supplying cysteine for the synthesis of glutathione

The chemical modifications that were made at the N- and C-terminals of the AnglV molecule and the resultant improvement in metabolic stability highlight the critical role played by exopeptidases in the metabolism of AnglV-derived molecules

Intranasal Delivery of Exendin-4 Confers Neuroprotective Effect Against Cerebral Ischemia in Mice