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These compounds are peptides composed of amino acids linked by peptide bonds ranging from 4113.6- 4813.5 Da

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Direct injection of 1 nmol GLP-1, exendin-4, or liraglutide to the ARC significantly suppressed food intake and body weight, with the effects observed over the 24 hours following injection [71,79,80]

According to the HE staining, the percentage of islets with immune cell infiltration was slightly increased in control diabetic mice at week 8 (Control 8 Week, 87.5% vs Control 0 Week, 0%, Fig