doi: 10.1016/j.freeradbiomed.2018.12.013 82 GreenYSFerreiraDSMFujaDGReichertECCamposARCowmanSJet al
Reactive oxygen species also contribute to the activation of the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, which facilitates the maturation and secretion of interleukin-1 (IL-1) and IL-18, further amplifying inflammation (Dominic et al., 2022)
Novel GLP-1-based Medications for Type 2 Diabetes and Obesity (Endocrine Reviews)
Reduces Inflammation Chronic inflammation is at the root of many health issues, including joint pain, autoimmune conditions, and neurodegenerative diseases
While the study was conducted on mice, it suggests that probiotics could augment GLP-1 RA therapys efficacy and help manage weight post-treatment
For Mounjaro, the medication should be discontinued when pregnancy is recognized