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Tras los ensayos de fase II, ya se le considera revolucionario
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These differences suggest that GCG cannot be uniformly characterized as either pro-tumorigenic or antitumorigenic in CRC
It is effective even in models of nerve damage
Epithelial-specific Arid1a deletion in mice preserves gland number but reduces FOXA2 and gland-specific genes (Lif, Spink3, Cxcl15), causing implantation and decidualization defects through disrupted LIF-STAT3-EGR1 signaling
While the efficacy data did not survive the Phase IIb primary endpoint, the safety dataset across 900 participants is unusual for a research peptide and is consistently cited as the basis for continued investigational interest
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