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Copper is an essential cofactor for superoxide dismutase (SOD), a primary antioxidant enzyme, and GHK-Cu has been studied in models examining oxidative stress mitigation

Their half-lives are 13 hours (LIRA) and 7 days (SEMA), allowing for daily and weekly subcutaneous administration, respectively, thanks to the structural modifications introduced.5,10 Effects on obesity and glycaemic control Both LIRA 3 mg and SEMA 2.4 mg have demonstrated a strong appetite-suppressing and satiety-promoting effect, as well as a delaying effect on gastric emptying.11,12 The SCALE programme highlighted the efficacy of LIRA 3 mg in reducing body weight and waist circumference13 and confirmed a reduction in HbA1c levels in individuals with diabetes, along with a decreased progression from prediabetes to diabetes after three years of treatment14 (Table 1)

The study also found that non-invasive blood tests and imaging measures reflected treatment-related improvements more clearly than liver biopsies

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Claims that Testagen restores natural testosterone production, rejuvenates, or has anti-aging effects are not established and should be read as unproven hypotheses

SF contributed to article writing, JB designed the study, organized sample acquirement from BioBanks, contributed to article writing