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The strong relationship between antioxidants and neurodegenerative diseases must therefore be given close attention

N-acetyl cysteine (NAC) is an antioxidant that enhances GSH synthesis, increases cysteine level and System X c activity, thereby inhibiting ferroptosis in Hb-induced ICH model and improving the prognosis of ICH mice (Karuppagounder et al., 2018)

GSH is required to recycle ascorbic acid in cultured liver cell lines

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Besides that, resveratrol treatment also induced SIRT1 and negatively regulated p53 signaling to increase cell proliferationrelated proteins, which promoted hepatocyte proliferation

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