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More #WPRDAY2026 Subscribe & Follow Novos expired semaglutide patent fires up weight-loss drug market The South African Health Products Regulatory Authority (SAHPRA) told Reuters that it is reviewing 12 applications for generic versions of semaglutide, the active ingredient in Novo Nordisks blockbuster diabetes and weight-loss medicines

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Although our point estimate may suggest a potential neutral or increased risk of MACE with combination therapy, this may reflect confounding by indication rather than a true association

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Targets Semaglutide is a longchain peptide (large MW, highly hydrophilic) requiring parenteral delivery or specialized oral formulations to protect against enzymatic and GI degradation