For broader context, semaglutide 2.4 mg produced roughly 10-18% body-weight reductions across the STEP program, while tirzepatide reported 16.0-22.5% reductions across the SURMOUNT-1 program
Heres what we know so far
Its a significant administrative burden on your doctor and can take weeks, or even months, to get a decision
Tirzepatide is a dual incretin receptor agonist, meaning it activates both the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

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The PlexusDx Precision Peptide Genetic Test identifies individual variations in the GLP1R gene and other appetite-control genes, revealing whether your genetics predispose you toward stronger or more modest medication responses