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The compound progressed through Phase 2 trials under ConjuChem in the mid-2000s for indications including HIV-associated lipodystrophy, but did not advance to a marketed therapeutic in any major jurisdiction

It has been reported that cells in a high mesenchymal or stem state are selectively sensitive to ferroptosis, which is a regulated cell death executed by lipid hydroperoxides ( Figures 3A, B and Supplementary Figures S2AC )

It should be mentioned that adverse side effects associated with intravitreal injections are uncommon but severe and include infectious endophthalmitis, cataract formation, retinal detachment, and elevated IOP

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For storage, it is imperative to keep the Glutanex in sealed, shaded containers and store them at room temperature, preferably between 1 to 30C

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