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Published by Cambridge University Press on behalf of The Nutrition Society Methotrexate (MTX, 4-amino-N10-methyl folic acid), an antagonist of folic acid, is commonly used as a chemotherapeutic drug to treat a variety of cancers and inflammatory diseases (Reference Puig1)

Insufficient maternal nutrition, especially during critical periods of embryonic and fetal development, manifests as an overall elevation of ovarian OS, which, along with impaired mitochondrial antioxidant defenses, may be responsible for these significantly decreased follicle numbers and resultant growth impediment of offspring [275]

Gas, loss of appetite, diarrhea, constipation

Jia SC, Li XY, Zheng SX, Wu G

Gola A, Knysak T, Mucha I, Musia W (2023) Synthesis, thermogravimetric analysis, and kinetic study of poly-N-isopropylacrylamide with varied initiator content

P., Muroy S., Brown S., Maughan S.C., Cobbett C.S., Van Montagu M., Inz D., May M.J., Sung Z.R