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For many, even shaving off a few minutes to fall asleep can be invaluable
It leads to changes in the structure of skin matrix proteins, such as collagen and elastin, and consequently, to loss of skin elasticity and firmness, the formation of wrinkles, and pigmentation disorders (116118)
These discussions are limited to in vitro and in vivo research models and do not imply approved applications, outcomes, or therapeutic use
Not for facial use.
Whichever protocol is chosen, tretinoin should always be paired with diligent daily broad-spectrum sunscreen , since retinoids increase photosensitivity
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