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Alterations in the gut microbiota, MGB axis, and neuro-immune system may be the cornerstone of the association between IBS and depression (Mudyanadzo et al., 2018)

The label does not cite the larger human observational studies published after 2017

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The peptide activates HGF/c-Met signaling cascades that upregulate synaptogenesis, dendritic spine growth, and NMDA receptor expression, and these changes continue autonomously once triggered

3) downstream effectors of mTOR signaling pathway

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