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Eur J Surg Oncol

Toxicity assays using Artemia salina indicated that aqueous, hydroalcoholic, methanolic, and dichloromethane fractions and compounds isolated from the aerial parts and leaves of A

This causes high oxidative stress, mitochondrial dysfunction, and cell death of the hepatocytes.[ref] As these cells die, inflammatory cascades perpetuate the oxidative stress, leading to bleeding, fibrosis, or possibly liver failure

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doi: 10.3389/fped.2018.00373 194 Nagy-SzakalDWilliamsBLMishraNCheXLeeBBatemanLet al