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The good news is that constipation responds well to basic management strategies

Recommend switching to a non-oral contraceptive or adding a barrier method for 4 weeks after starting or increasing the dose

Anti-angiogenic approaches have improved the efficacy of chemotherapy and targeted therapy for breast cancer

Regular physical activity, even gentle walking, stimulates bowel motility

Relation to dietary and social habits, education, physical activity, height, and weight

The clinical outcomes they produce, 15 to 22 percent average body weight reduction over 68 weeks, are several times better than any previous weight loss medication