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doi:10.1056/NEJMoa1700459 Adiels M, Olofsson SO, Taskinen MR, Boren J

This deamination produces aldehydes that participate in cross-linking reactions that link adjacent collagen or elastin molecules, giving mature collagen and elastin their characteristic mechanical properties

Washington, DC: US Departments of agriculture and health and human services, 2015

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However, although these activated progenitors produce mature OLGs in the cuprizone model, the process fails in EAE, suggesting that inflammation (in EAE) may lead to an overactivation of GPR17, thereby preventing the terminal differentiation of OPCs (Coppolino et al., 2019)

Lyoprotectants prevent bilayer damage, leakage of encapsulated materials and vesicle aggregation