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327,328 Combining FK866 with the PARP inhibitor, olaparib, results in cell death through the suppression of the NAD + serving as the substrate of PARP in triple-negative breast cancer or colon cancer cell lines as well as in vivo models, with the combinatorial treatment inducing negligible systemic
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Mansilla S, Priebe W, Portugal J (2006) Mitotic catastrophe results in cell death by caspase-dependentand caspase-independent mechanisms
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