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[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Pathogenic lysosomal depletion in Parkinson's disease

Animal studies have provided some of the earliest clues

CBS News (2023)

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Under baseline conditions, the renal clearance of L-carnitine (1-3 mL/min) is substantially less than glomerular filtration rate (GFR), indicating extensive (98-99%) tubular reabsorption