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doi: 10.1155/MI.2005.245

Influence of the Th1 cytokine environment on CCL5 production from langerhans cells

in vitro experiments showed that SGK1 knockdown alleviated erastin-induced downregulation of Slc7a11, GPX4, GSH, and GSSG, while reducing lipid peroxidation, iron accumulation, and mitochondrial damage upregulation, suggesting that SGK1 modulates ferroptosis processes through inflammatory pathways in CHD (44)

In contrast to well-known system Xc- inhibitors such as erastin and sulfasalazine, sorafenib failed to induce ferroptosis in a series of cancer cells

doi:10.1080/03007995.2019.1586401 Ghlichloo I, Gerriets V