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Sonelokimab, lutikizumab, and adalimumab showed the highest HiSCR-50 response rates in moderate to severe hidradenitis suppurativa, per a network meta-analysis in JAMA Dermatology

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(2018) 5(1):e000771

The microbes in the large intestine incorporate cobalt into cobalamin, which supports methylation reactions and normal protein, carbohydrate, and fat metabolism

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