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The clinical studies showing efficacy used concentrations in the range that produces measurable results without irritation

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Epub 2020 Dec 28

To directly address the glutathione depletion characteristic of ME/CFS and Long COVID, HM Complex provides a synergistic triad of N-acetyl-l-cysteine (NAC), l-methionine, and alpha lipoic acid (ALA)

Duryee MJ, Klassen LW, Schaffert CS, Tuma DJ, Hunter CD, Garvin RP, et al

An increasing body of evidence suggests that oxidative stress, which results in an excessive generation of reactive oxygen species (ROS), has a key role in the pathogenesis of hypertension