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Importantly, the Nrf2 signaling pathway has been linked to safeguarding against myocardial injury induced by ischemia/reperfusion (I/R), protecting against oxidative stress, and addressing electrolytes imbalances 45

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[10] There is no UL for riboflavin because no toxicity has been reported when an excess amount has been consumed through foods or supplements

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Melatonin exerts protective effects in an ILC2-biased model of allergic airways disease, even in the presence of canonical receptor blockade To determine whether the protective effects of melatonin extended beyond allergen-driven disease, we next employed an ILC2-biased IL-33 model of allergic airways inflammation ( Figure 2A )