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Binding of iodinated ornithine vasotocin analog ([ 125 I] OVT) to oxytocin receptors was performed following methods from Insel et al

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The mechanism remains neurocentric rather than systemic hormonal

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While NAC does not treat progesterone hypersensitivity itself, it may help reduce inflammatory burden and oxidative stress associated with immune activation in autoimmune progesterone dermatitis (APD)