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A daily combination of 1 mg of folate, 7.2 mg of vitamin B6, and 20 ug of vitamin B12 effectively reduced plasma homocysteine levels in these individuals.42 Many patients with inborn errors of metabolism that affect homocysteine metabolism, such as CBS deficiency, require a low-protein diet in which methionine-rich foods such as meat, fish, eggs, and dairy foods are restricted

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