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Endocrinology 162:bqab185

Glucagon, secreted by alpha cells in the pancreas, is an important hormone that promotes the release of glucose from the liver into the bloodstream (Robertson, 2023)

doi: 10.1007/s004150050522 20 Vallat-DecouvelaereAVWassefMLotGCatalaMMoussalamMCaruelNet al

Iron-deficiency or inadequate pyridoxine or riboflavin status will decrease the conversion of tryptophan to niacin and may contribute to deficiency, due to an interdependence of coenzymes in the niacin production pathway

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The exact reason why this happens is not fully understood