This disorder is closely linked to culturally reinforced masculine ideals, especially in Western societies, where muscularity is associated with strength, dominance, and masculinity
These shifts in metabolism are often global across the brain, e.g., in a meta-analysis, the conditions of eyes closed versus open, sevoflurane and desflurane anesthesia, and comas of varying levels all demonstrated a global shift, whereas only congenitally blind versus sighted demonstrated localized changes [61]
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Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo
Likewise, the possibility that hepatocyte subpopulations at the onset of culture influence differential responses to microenvironmental cues cannot be excluded
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