Currently, there are 9 GLP-1RAs approved by the FDA, widely used for the treatment of type 2 diabetes
Tirzepatide expanded the field from one receptor (GLP-1) to two (GLP-1 + GIP)
Timelines differ by person, dose, and medication, and clinical trials titrate doses gradually over months
Therefore, it is controversial whether GLP-1RAs therapy could prevent and treat diabetic osteoporosis and fragility fractures in clinical practice
The sample was 92.9% men, 68.9% non-Hispanic White race, 15.0% non-Hispanic Black race, and 5.3% Hispanic ethnicity
Call your clinician if you faint, experience repeated falls, have chest pain or difficulty breathing, show new severe confusion, or cannot keep fluids down for 24 hours