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Las condiciones metablicas en la mediana edad, como la obesidad y la diabetes, son factores de riesgo bien establecidos y modificables para el desarrollo de demencia (Comisin Lancet sobre factores de riesgo de demencia)

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1 Moreover, obesity has been reported to be associated with a less favorable response to disease-modifying therapies

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If you have a history of recurrent or severe hypoglycaemia, particularly hypoglycaemia unawareness, your prescribing clinician will need to conduct a thorough risk-benefit assessment