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The SELECT trial (2023) further demonstrated a 20% reduction in major adverse cardiovascular events, adding a cardioprotective dimension

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Exception: Ghee (clarified butter) contains minimal protein and may be tolerated

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It is currently the phase II drug associated with the greatest weight reduction, achieving a 24% decrease (28.5% in women) after 48 weeks with a weekly dose of 12 mg55 (Table 1), and providing significant benefits in the control of cardiovascular risk factors and the reduction of MASLD56 (Fig