Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (which can be caused by ingestion of corrosives, extensive tumors, and conditions associated with gastric atrophy, such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy) Structural lesions leading to vitamin B 12 deficiency, including regional ileitis, ileal reactions, and malignancies Competition for vitamin B 12 by intestinal parasites or bacteria
CA Cancer J Clin (2021) 71(3):20949
Many people choose to take vitamin B12 earlier in the day and vitamin D with a meal, but timing can be adjusted based on personal preference and routine
Blocking NNMT is expected to raise SAM availability, but SAM participates in many cellular processes, so research must establish that selectively raising it does not perturb other methylation pathways
Many patients notice changes within days to a few weeks, depending on how deficient they were and how consistent the protocol is
Promotion of Neurogenesis By stimulating the growth of new neurons (neurogenesis), Dihexa contributes to the overall health and functionality of the brain, which is crucial for cognitive processes