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The key insight is that semaglutide does not target one system in isolation

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Monitor renal function in patients reporting adverse reactions to RYBELSUS or OZEMPIC tablets that could lead to volume depletion, especially during dosage initiation and escalation of RYBELSUS or OZEMPIC tablets

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The STEP 4 trial showed that patients who stopped semaglutide after successful weight loss regained approximately two-thirds of their lost weight within one year

Highlights of Prescribing Information: Wegovy (semaglutide) injection, for subcutaneous use Wegovy (semaglutide) tablets, for oral use