This may result in the body storing more fat, particularly visceral fat that surrounds internal organs, which is particularly dangerous
There is limited research on microdosing GLP-1, so the bodys long-term response remains unpredictable and there may be adverse side effects, Zimmermann adds
While some preclinical studies suggest GLP-1 receptor agonists may have anti-inflammatory properties, it is important to emphasise that there is no clinical evidence demonstrating benefit in fibromyalgia patients
HR, hazard ratio
A comprehensive review of 118 trials found clinically meaningful benefits, and the Cochrane Review of 50 trials with nearly 8,000 participants confirmed that naltrexone reduces the risk of heavy drinking
However, weight loss from semaglutide may reduce mechanical stress on joints and muscles, potentially easing fibromyalgia symptoms indirectly